Category: Health Testing

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ANNOUNCING A GENETIC TEST FOR SHAR-PEI AUTOINFLAMMATORY DISEASE (SPAID)

A validated genetic test is now available to measure the copy number variant (CNV) linked to Shar-Pei Autoinflammatory Disease (SPAID), reveals an international collaboration lead by scientists and veterinarians at Uppsala, Sweden and Wurtsboro, New York, USA. Details were published in the April 23 edition of the open-access journal BMC Genomics. http://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-016-2619-0 This work represents the third step in the group’s ongoing research into the relationship between the Shar-Pei dog breed’s unique skin appearance and a complex hereditary syndrome, SPAID. In 2011, the team first reported the existence of a duplicated segment of DNA upstream of the gene hyaluronan synthase...

Genetic Tests

Fueled by the explosive advancements in biology, genetics, biochemistry, molecular biology and technology we have entered a time of significant advances in the study of genetic diseases in dogs. The completion of the Canine Genome Project will only accelerate our understanding in this area. Key to the practical usage of knowledge in the field of canine genetic diseases is the development and application of DNA-based genetic tests. DNA-based genetic tests identify differences in DNA sequences and are of two different types. The mutation-based test recognizes disease-causing mutations while the linked polymorphism test recognizes DNA differences that are near the disease-causing...